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Reproductive Toxicity Studies

IIRT provides facility for reproductive toxicity study which is a part of scientific investigation, designed to assess the potential adverse effects of a substance on the reproductive system. This study typically involves exposing test subjects, such as laboratory animals like rats or rabbits, to varying doses of the substance over a specified period. Researchers then observe and analyze various parameters related to reproductive health, including fertility, gestation, embryonic development, and offspring health.

The goal of a reproductive toxicity study is to determine if exposure to the substance being tested has any detrimental effects on the reproductive capacity of the test subjects or on the health of their offspring. This information is crucial for regulatory agencies, manufacturers, and healthcare providers to assess the safety of the substance and make informed decisions about its use.

Reproductive toxicity studies are an essential component of the overall safety assessment process for chemicals, pharmaceuticals, pesticides, and other substances that may come into contact with humans or the environment. The results of these studies can influence regulatory decisions regarding the approval, labeling, and use of these substances.

IIRT offers the following Reproductive Toxicity Studies:

  • Prenatal Developmental Toxicity Study, OECD 414
  • Two-generation Reproduction Toxicity Study, OECD 416
  • Reproduction/Developmental Toxicity Screening Test, OECD 421
  • Combined Repeated Dose Toxicity Study with the Reproduction/ Developmental Toxicity Screening Test, OECD 422
  • Developmental Neurotoxicity Study, OECD 426
  • Extended One-Generation Reproduction Toxicity Study, OECD 443

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