toxicityindia

Invitro Toxicity Studies

Our scientists and research associates help in conducting In-vitro Toxicity Studies. We are one of the renowned and reputed institutes engaged in providing highly reliable research-related services.

An in vitro toxicity study is a type of scientific investigation conducted in a controlled laboratory setting using isolated cells, tissues, or organs outside of a living organism. 

The primary goal of an in vitro toxicity study is to assess the potential harmful effects of a substance on living cells or tissues without the need for animal testing. These studies can provide valuable insights into the mechanisms of toxicity and help prioritize substances for further testing or regulatory evaluation.

In vitro toxicity studies are widely used in the fields of pharmacology, environmental science, and toxicology to screen new drugs, chemicals, and environmental pollutants for potential safety concerns. They are also instrumental in the development of alternative methods to reduce the reliance on animal testing in regulatory toxicology assessments.

We provide the following In-vitro Toxicity Studies:

1. Skin Absorption: in vitro method, OECD 428

2. In vitro Skin Corrosion: Transcutaneous Electric Resistance Test (TER), OECD 430

3. In vitro Skin Corrosion: Reconstructed Human Epidermis  (RHE) Test, OECD 431

4. In vitro 3T3 NRU Phototoxicity Test, OECD 432

5. In vitro Membrane Barrier Test Method for Skin Corrosion, OECD 435

5. In vitro Skin irritation: Reconstructed Human Epidermis Test Method, OECD 439

6. In vitro Skin Sensitization, OECD 442D

7. In vitro Skin Sensitization: In vitro skin sensitization assays addressing the key events on activation of dendritic cells on the adverse outcome pathway for skin sensitization, OECD 442E

8. In vitro Mammalian Chromosome Aberration Test, OECD 473

9. In vitro Mammalian Cell Gene Mutation Tets using the Hprt and xprt genes, OECD 476

10. In vitro Mammalian Cell Micronucleus Test, OECD 487

11. In vitro Thymidine Kinase Mutation Test, OECD 490

12. In vitro Macromolecular Test, OECD 496

13. In vitro Phototoxicity: Reconstructed Human Epidermis Phototoxicity Test Method, OECD 498

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